Which statement about anti-A,B reagents is true?

Which statement about anti-A,B reagents is true?

• A. It is used to confirm group O individuals
• B. It is used exclusively in reverse grouping
• C. It detects anti-A antibodies
• D. It is used only for neonatal typing

Answer: (A)

Anti-A,B reagents contain antibodies against both A and B antigens and are used in forward ABO typing to detect whether red cells express A or B antigens. If the cells show no agglutination with this reagent, it indicates the absence of A and B antigens, which is consistent with blood group O. That’s why this statement is correct: the reagent helps confirm group O by showing a lack of A and B antigens. It isn’t used exclusively in reverse grouping (that would be a different part of typing), it doesn’t detect anti-A antibodies (those would be antibodies in plasma, not surface antigens on cells), and it isn’t restricted to neonatal typing.

Anti-A,B reagents contain antibodies against both A and B antigens and are used in forward ABO typing to detect whether red cells express A or B antigens. If the cells show no agglutination with this reagent, it indicates the absence of A and B antigens, which is consistent with blood group O. That’s why this statement is correct: the reagent helps confirm group O by showing a lack of A and B antigens. It isn’t used exclusively in reverse grouping (that would be a different part of typing), it doesn’t detect anti-A antibodies (those would be antibodies in plasma, not surface antigens on cells), and it isn’t restricted to neonatal typing.